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Peptide Insights provides information about peptides based on published scientific research and clinical literature. This content is designed to help you understand the science, not to guide personal medical decisions.
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Egrifta · GHRH Analog
FDA-approved GHRH analog for visceral fat reduction
Typical Dose
1–2 mg per day
Route
Subcutaneous
Frequency
Once daily, in the morning
Cycle
3–6 months
Tesamorelin is a synthetic version of a hormone your brain naturally produces to tell your pituitary gland to release growth hormone. It is FDA-approved for a specific condition that causes excess belly fat in HIV patients, but it is also used off-label by people who want to reduce deep abdominal fat (called visceral fat) and improve their body composition. Visceral fat is the dangerous kind that wraps around your organs — not just the kind you can pinch.
Tesamorelin tells your pituitary gland (a small gland at the base of your brain) to release growth hormone in natural pulses, the same way your body does it on its own. That growth hormone then signals your body to break down stored fat for energy, particularly the deep belly fat around your organs. It also raises IGF-1, a growth factor that supports muscle maintenance and overall body composition.
Typical Dose
1–2 mg per day
Dose Range
1–2 mg/day
Frequency
Once daily, in the morning
Route
Subcutaneous injection
Cycle Length
3–6 months
CLINICAL NOTES
Best taken in the morning on an empty stomach. Results are typically seen within 3 months.
IMPORTANT DISCLAIMER
This information is for educational purposes only. Always consult a qualified healthcare provider before starting any peptide protocol. Individual responses vary and medical supervision is recommended.
Tesamorelin is a GHRH analog best stacked with GH secretagogues for amplified GH pulses.
GHRH + GHRP is the classic GH optimization stack. Tesamorelin + Ipamorelin produces synergistic GH release.
CJC-1295 extends GH pulse duration while tesamorelin initiates the pulse — a powerful combination.
AOD-9604 adds targeted fat-burning to tesamorelin's visceral fat reduction.
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